PathoPic – image database / PathoPic ID 11161 - Atypische apokrine Adenose der Mamma

Zellreiche Adenose mit einer Mischung von normal grossen und atypischen apokrin differenzierten Zellen. Mitosen, oder Nekrosen sind nicht vorhanden. Einige Zellen zeigen eine apokrine Sekretion.

52 jährige Patientin mit unklarem Herdbefund der Mamma perimamillär.

Atypical apocrine adenosis is a rare lesion (<1% of cases). Women found to have atypical apocrine adenosis were, on average, older than were other patients with benign breast disease, however, there does not seem to be an association with age and risk for developing carcinoma in patients diagnosed with atypical apocrine adenosis, as previously suggested; and atypical apocrine adenosis does not appear to be an aggressive lesion and should not be regarded as a direct histologic precursor to breast carcinoma. Arch Pathol Lab Med. 2012 Feb;136(2):179-82. Atypical apocrine adenosis of the breast: long-term follow-up in 37 patients. Fuehrer N et al. PMID: 22288965