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Infiltrates of a poorly differentiated carcinoma, compatible with metastasis of a urothelial carcinoma.
Haematoxylin & Eosin (H&E)
85 years
85-year old male patient who reports hematemesis. Billroth type I resection 50 years ago for a duodenal ulcer. The present endoscopy shows an ulcerated gastric tumor.
Several fragments with extensive infiltrates of a poorly differentiated carcinoma. There is no discernible residual gastric mucosa. Note the heavily desmoplastic stroma and signs of ulceration.
IHC: CK7 positive. Weak positivity for CK5/6, CK13 and CK14. Negativity for p63 and CK20. In addition, the patients history included a urothelial carcinoma of the bladder.
Philippe Brunner, University of Basel
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