1546
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Type I refractory sprue
Duodenum
CD8
60 years
female
The patient does not comply with a gluten free diet since 6 months. Anti-gliadine and anti-transglutaminase antibodies are in a normal range. Gastroscopy showed no major findings.
Intraepithelial lymphocytosis without villous atrophy of the duodenal mucosa (Marsh type I). Slight hypertrophy of the crypts. In the IHC staining most lymphocytes are CD3 and CD8 double positive.
For HE stain see slide ID: 1545 For CD3 IHC see slide ID: 1547
Joël Gsponer
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