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Sclerosing mediastinitis
Haematoxylin & Eosin (H&E)
51 years
51 years old woman. Mediastinal tumor with compression of the vena cava superior.
Collagenous, hypocellular lesion
Idiopathic, can be associated with Histoplasma capsulatum (North America). No IgG4 association described. Exclusion of differential diagnosis is important (desmoid tumor, desmoplastic mesothelioma, inflammatory myofibroblastic tumor, lymphoma with sclerosis, solitary fibrous tumor). Good prognosis if the resection is complete. Otherwise recurrence and progressive course.
Huber Bettina
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