1650
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Desmoid tumor, beta-catenin
Mediastinum
Haematoxylin & Eosin (H&E)
beta-Catenin
28 years
female
Nuclear positivity of tumor cells for beta-catenin on immunhoistochemistry
Nuclear expression of beta-catenin because of a somatic mutation in the beta-catenin gene (CTNNB1) or an inactivating mutation of the APC gene (Gardner-type FAP) with intranuclear accumulation of beta-catenin protein.
Huber Bettina
http://pathorama.ch/vSlides/Desmoid_tumor_beta_catenin-1650.html
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