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Nodular and beginning diffuse infiltration by chronic lymphatic leukemia (infiltration volume 80%).
Bone Marrow
Haematoxylin & Eosin (H&E)
70 years
70-year old male patient with a CLL diagnosed 4 months ago. Bone marrow biopsy was performed before starting treatment due to B-symptoms and symptomatic lymphadenopathy.
Hypercellular bone marrow (70-80%) showing multiple nodular, at times diffuse infiltrates of mature small lymphoid cells. There is a partial displacement of the normal hematopoiesis which does not show features of dysplasia.
Philippe Brunner, University of Basel
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